Paʻi ʻia e: West China School of Pharmacy Sichuan University

Maʻiʻo nui: ʻO ka mālama pono ʻana i ka maʻi o Alzheimer (AD) ua keʻakeʻa ʻia e ke komo ʻana o ka pale koko-lolo a me ka hāʻawi ʻole ʻana i nā lāʻau lapaʻau i loko o ka lolo.Eia kekahi, paʻakikī nā ʻano pathological o AD a pili i ka dysfunction o nā ala he nui, e kaupalena ana i ka pono o nā mea lapaʻau hoʻokahi.Hoʻolālā kēia ʻatikala i kahi DGL-based siRNA a me D-peptide (Dp) -loaded nanoparticles, hiki ke hoʻopaʻa a komo i ka pale koko-lolo, komo i ka parenchyma lolo, a hōʻiliʻili hou i nā lesions AD, e hoʻomaikaʻi i ka pono o ke komo ʻana o ka lāʻau i loko o ka lolo, hoʻomaikaʻi i ka cognitive dysfunction a me neuronal pōʻino i hana ʻia e AD.Heluhelu hou aku

Paʻi ʻia e: West China School of Pharmacy Sichuan University

Maʻiʻo nui: ʻO ka microenvironment hypoxic o nā maʻi koko paʻa he mea koʻikoʻi no ka metastasis maʻi kanesa.No laila, ʻo ka hoʻomaikaʻi ʻana i ka hypoxia ma ka pūnaewele tumor kahi ala kūpono e pale ai i ka metastasis tumor.Ke hoʻohālikelike ʻia me ka pepehi pololei ʻana i nā cell tumor, hiki i ka hoʻoponopono hou ʻana i ka microenvironment tumor ke pale i ka hanana ʻana a me ka ulu ʻana o nā maʻi mai nā ʻano he nui, ʻo ia ke ʻano o ka lāʻau lapaʻau.Ua hoʻolālā kēia haʻawina i kahi mea lawe i hiki ke neʻe kūʻokoʻa a hiki ke hoʻomau i ka oxygen i loko o ka ʻōpū.I ka manawa like, no ka manawa mua, ua manaʻo ʻia kahi hoʻolālā hui o ka hoʻomaikaʻi ʻana i ka hypoxia a me ka pale ʻana i ka glycolysis e hoʻohuli piha i ka microenvironment tumor a hoʻokō i ka hopena o ka pale ʻana i ka metastasis maʻi umauma.Heluhelu hou aku

Paʻi ʻia e: College of Life Science Sichuan University

Maʻiʻo nui: ʻO ke ala hōʻailona abscisic acid (ABA) pili i nā pane o nā mea kanu i ka maloʻo a me ke koʻikoʻi paʻakai.ʻOiai ua wehewehe ʻia ke ala hōʻailona ABA ma Arabidopsis, ʻaʻole i ʻike ʻia ma ka poplar lāʻau.Ma kēia haʻawina, ua hōʻike ʻia ka loiloi genome-ākea o nā poplar U-box genes i ka U-box E3 ubiquitin ligase gene PalPUB79 i hoʻoulu nui ʻia ma hope o ka maloʻo, salinity a me ka hōʻailona ABA.Ua hōʻike ʻia nā hopena ua hoʻoponopono maikaʻi ʻo PalPUB79 i ke ala hōʻailona ABA, e hāʻawi ana i nā ʻike hou i ke ʻano hana e hoʻonui ai ʻo PalPUB79 i nā pane koʻikoʻi i hoʻopili ʻia e ABA i ka poplar lāʻau.Heluhelu hou aku

ʻIkepili Huahana

ʻO ka PCR Easyᵀᴹ-SYBR Green I Kit

REF: QP-01012/QP-01014